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ABMapper: A suffix array-based tool for multi-location searching and splice-junction mapping
Date Issued
2011
Journal
Bioinformatics
ISSN
14602059
Citation
Bioinformatics, 2011, vol. 27( 3), pp. 421 - 422, Article number btq656
Type
Peer Reviewed Journal Article
Abstract
Summary: Sequencing reads generated by RNA-sequencing (RNA-seq) must first be mapped back to the genome through alignment before they can be further analyzed. Current fast and memory-saving short-read mappers could give us a quick view of the transcriptome. However, they are neither designed for reads that span across splice junctions nor for repetitive reads, which can be mapped to multiple locations in the genome (multi-reads). Here, we describe a new software package: ABMapper, which is specifically designed for exploring all putative locations of reads that are mapped to splice junctions or repetitive in nature. © The Author(s) 2010. Published by Oxford University Press.
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