Dr. LAM Yin-Hung, BessBessDr. LAM Yin-Hung2024-04-172024-04-172023Lam, Y. H. (2023 Nov 17). The relationship between psychopathy and aggression: A potential neural mediator. ASC Annual Meeting 2023, Philadelphia, PA.http://hdl.handle.net/20.500.11861/9474https://convention2.allacademic.com/one/asc/asc23/index.php?cmd=Online+Program+View+Paper&selected_paper_id=2075718&PHPSESSID=doms7ebsaeua4284m53s7c7fuuBackground Prior research has found that psychopathy is positively associated with aggression. The present study examined whether entorhinal cortex which is involved in perceptual function and attention partly explain this relationship.<br> Method Forty participants, aged between 12 and 43 years of age, were recruited from a community sample. All participants completed the Dirty Dozen Scale and Reactive-Proactive Aggression Questionnaire for their psychopathy and aggressiveness were administered. Their structural brain correlates using MRI were also measured.<br> Results Correlational and mediation analyses were performed. As hypothesized, psychopathy was positively correlated with aggression (r= 0.39, p< 0.05). Psychopathy was positively related to the right entorhinal gray matter volumes while aggression has a negative association (p< 0.05). Mediation analysis showed that right entorhinal gray matter volumes significantly and partly mediated the relationship between psychopathy and aggression (p< 0.05). The results were not significant for the left side of entorhinal gray matter volumes.<br> Conclusion These pilot findings suggest that entorhinal gray matter volumes (especially the right side) which are involved in perceptual ability may be mediator explaining the relationship between psychopathy and aggression. These findings help us to gain a better understanding of the neural mediator underlying the relationship between psychopathy and aggression.enConference Paper