Please use this identifier to cite or link to this item:
http://hdl.handle.net/20.500.11861/8645
DC Field | Value | Language |
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dc.contributor.author | Leung, Yvonne | en_US |
dc.contributor.author | Barzilai, Nir | en_US |
dc.contributor.author | Batko-Szwaczka, Agnieszka | en_US |
dc.contributor.author | Beker, Nina | en_US |
dc.contributor.author | Boerner, Kathrin | en_US |
dc.contributor.author | Brayne, Carol | en_US |
dc.contributor.author | Brodaty, Henry | en_US |
dc.contributor.author | Cheung, Karen Siu Lan | en_US |
dc.contributor.author | Corrada, María M. | en_US |
dc.contributor.author | Crawford, John D. | en_US |
dc.contributor.author | Galbussera, Alessia A. | en_US |
dc.contributor.author | Gondo, Yasuyuki | en_US |
dc.contributor.author | Holstege, Henne | en_US |
dc.contributor.author | Hulsman, Marc | en_US |
dc.contributor.author | Ishioka, Yoshiko Lily | en_US |
dc.contributor.author | Jopp, Daniela | en_US |
dc.contributor.author | Kawas, Claudia H. | en_US |
dc.contributor.author | Kaye, Jeff | en_US |
dc.contributor.author | Kochan, Nicole A. | en_US |
dc.contributor.author | Dr. LAU Hi Po, Bobo | en_US |
dc.contributor.author | Lipnicki, Darren M. | en_US |
dc.contributor.author | Lo, Jessica W. | en_US |
dc.contributor.author | Lucca, Ugo | en_US |
dc.contributor.author | Makkar, Steve R. | en_US |
dc.contributor.author | Marcon, Gabriella | en_US |
dc.contributor.author | Martin, Peter | en_US |
dc.contributor.author | Meguro, Kenichi | en_US |
dc.contributor.author | Milman, Sofiya | en_US |
dc.contributor.author | Poon, Leonard W. | en_US |
dc.contributor.author | Recchia, Angela | en_US |
dc.contributor.author | Ribeiro, Oscar | en_US |
dc.contributor.author | Riva, Emma | en_US |
dc.contributor.author | Rott, Christoph | en_US |
dc.contributor.author | Sikkes, Sietske AM | en_US |
dc.contributor.author | Skoog, Ingmar | en_US |
dc.contributor.author | Stephan, Blossom | en_US |
dc.contributor.author | Szewieczek, Jan | en_US |
dc.contributor.author | Teixeira, Laetitia | en_US |
dc.contributor.author | Tettamanti, Mauro | en_US |
dc.contributor.author | Wilczyński, Krzysztof | en_US |
dc.contributor.author | Sachdev, Perminder | en_US |
dc.date.accessioned | 2023-11-17T10:19:13Z | - |
dc.date.available | 2023-11-17T10:19:13Z | - |
dc.date.issued | 2023 | - |
dc.identifier.citation | Alzheimer's and Dementia, 2023, Vol.19(6), pp. 2265-2275. | en_US |
dc.identifier.issn | 15525260 | - |
dc.identifier.uri | http://hdl.handle.net/20.500.11861/8645 | - |
dc.description.abstract | Introduction: There are limited data on prevalence of dementia in centenarians and near-centenarians (C/NC), its determinants, and whether the risk of dementia continues to rise beyond 100. Methods: Participant-level data were obtained from 18 community-based studies (N = 4427) in 11 countries that included individuals ≥95 years. A harmonization protocol was applied to cognitive and functional impairments, and a meta-analysis was performed. Results: The mean age was 98.3 years (SD = 2.67); 79% were women. After adjusting for age, sex, and education, dementia prevalence was 53.2% in women and 45.5% in men, with risk continuing to increase with age. Education (OR 0.95;0.92–0.98) was protective, as was hypertension (odds ratio [OR] 0.51;0.35–0.74) in five studies. Dementia was not associated with diabetes, vision and hearing impairments, smoking, and body mass index (BMI). Discussion: Among the exceptional old, dementia prevalence remains higher in the older participants. Education was protective against dementia, but other factors for dementia-free survival in C/NC remain to be understood. © 2022 The Authors. Alzheimer's & Dementia published by Wiley Periodicals LLC on behalf of Alzheimer's Association. | en_US |
dc.language.iso | en | en_US |
dc.relation.ispartof | Alzheimer's and Dementia | en_US |
dc.title | Cognition, function, and prevalent dementia in centenarians and near-centenarians: An individual participant data (IPD) meta-analysis of 18 studies | en_US |
dc.type | Peer Reviewed Journal Article | en_US |
dc.identifier.doi | 10.1002/alz.12828 | - |
item.fulltext | No Fulltext | - |
crisitem.author.dept | Department of Counselling & Psychology | - |
Appears in Collections: | Counselling and Psychology - Publication |
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